U.S., July 18 -- ClinicalTrials.gov registry received information related to the study (NCT07071727) titled 'Short Course of Radiotherapy Prior to Surgery of Soft Tissue Sarcomas' on July 08.
Brief Summary: Based upon the preliminary data derived from first SCOPES clinical trial and the results of patients treated during the recent COVID-19 pandemic, patients with soft tissue sarcomas (STS) can be preoperatively irradiated in a modestly hypofractionated schedule of 14 x 3 Gy. From a toxicity and efficacy point of view, this regimen equals the outcomes after a conventionally fractionated regimen of 25 x 2 Gy in five weeks. Moreover, the rationale for investigating (modest) hypofractionation in the clinic comes both from a logistic point of ...