U.S., Nov. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07225777) titled 'Sex Differences in Neurobehavioral Response to THC' on Nov. 05.
Brief Summary: This study investigates sex differences in reward processing following acute THC administration in adults with cannabis use disorder (CUD). Using multimodal neuroimaging (MRS and fMRI), the study will assess glutamate levels in the nucleus accumbens and striatal BOLD response to monetary reward anticipation. Participants will complete two counterbalanced dosing sessions (oral THC 40 mg vs. placebo).
Study Start Date: Jan. 01, 2026
Study Type: INTERVENTIONAL
Condition:
Cannabis Use Disorder
Intervention:
DRUG: Dronabinol
Oral dronabinol capsules (40...