U.S., June 25 -- ClinicalTrials.gov registry received information related to the study (NCT07033676) titled 'Serum miR-455-5p and Cardiac Structure and Function Parameters in Patients With Hypertensive Heart Disease' on Dec. 08, 2023.

Brief Summary: Hypertensive heart disease (HHD) is the leading cause of mortality and morbidity worldwide. In 2017, the prevalence of HHD worldwide was 217.9 per 100,000 people, an increase of 7.4% over 1990, which has brought huge financial burden and social and economic losses to the world. Therefore, HHD is a major public health challenge worldwide. In our previous studies, we found that miR-455-5p, a microRNA, could functioned as an inducer to promote cardiac hypertrophy. Because cardiac hypertrophy was a...