U.S., Jan. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07355842) titled 'Role of Slow Waves in the Progression of Neurodegeneration in Isolated REM Sleep Behavior Disorder' on Dec. 22, 2025.
Brief Summary: This study tests whether enhancing deep sleep with gentle sounds at night can slow progression in people with iRBD or early Parkinson's disease. Participants wear a sensor headband and headphones for 18 months. Four assessments including mobility, memory, imaging (PET/MRI), lumbar puncture, and blood tests are assessed.
Study Start Date: Jan. 15
Study Type: INTERVENTIONAL
Condition:
Parkinson Disease
REM Sleep Behavior Disorder (iRBD)
Intervention:
DEVICE: Tosoo Axora
Phase Targeted Auditory Sti...