U.S., Oct. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07203521) titled 'RK-4 Intracalvariosseous Injection in Treatment of Acute Large Hemispheric Infarction' on Sept. 23.

Brief Summary: An open-label, blinded phase II study investigating the treatment of acute large hemispheric infarction by transcranial bone marrow injection of RK-4 injection For subjects with acute large hemispheric infarction who are contraindicated to vascular recanalization or have poor response to vascular recanalization therapy, the safety, tolerability, and PK characteristics of RK-4 injection injected into the brain cell marrow through the cranial bone marrow will be preliminarily evaluated, and the efficacy will be preliminari...