U.S., Jan. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07376538) titled 'Response-Based Local Therapy for Regionally Advanced Breast Cancer: A Phase II Study' on Jan. 20.
Brief Summary: The goal of this interventional clinical trial is to evaluate if an individualized treatment strategy (involving radiation boost, surgery, and systemic consolidation) can improve progression-free survival in patients with breast cancer presenting with positive ipsilateral supraclavicular (ISLN) and/or internal mammary lymph nodes (IMLN).
The main questions it aims to answer are:
Is individualized hypofractionated radiotherapy with a local boost safe and effective when adjusted by the response to neoadjuvant treatment?
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