U.S., July 16 -- ClinicalTrials.gov registry received information related to the study (NCT07065799) titled 'Respiratory Strategies in COPD Patients With Persistent Hypercapnia Following Exacerbation' on May 17, 2024.
Brief Summary: This multicenter, cross-over study aims to investigate the effects of two different respiratory strategies, the use of high flow nasal cannula (NHF) and the use of home mechanic ventilation (HMV), both associated with standard oxygen therapy, in patients with COPD and persistent hypercapnia following a severe acute exacerbation.
The purpose is to evaluate whether the clinical benefits, in terms of reduction in PaCO2 levels, resulting from the use of NHF are non-inferior to those obtained from the use of HMV.
...