U.S., Sept. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07156331) titled 'Research on Effects of Drugs on Body Composition and Function With Imaging in Diabetes' on Aug. 07.
Brief Summary: One downside of diabetes weight loss drugs like GLP-1RA and GLP-1RA/GIP, is that they can cause muscle loss, which is especially risky for older adults or those already prone to frailty and falls. There is also concern that GLP-1RA might affect bone health, possibly leading to weaker bones and increased risk of fractures. To prevent these issues, doctors need to better predict who is most at risk of muscle and/or bone loss. That way, doctors can adjust patient management-like adding targeted physical therapy, or bone-pr...