Clinical Trial: Repeated Mesenchymal Stem Cell Therapy for Radiation-Induced Hyposalivation and Xerostomia in Head and Neck Cancer Survivors

U.S., Dec. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07290946) titled 'Repeated Mesenchymal Stem Cell Therapy for Radiation-Induced Hyposalivation and Xerostomia in Head and Neck Cancer Survivors' on Nov. 18.

Brief Summary: Dry mouth leads to debilitating symptoms 24/7. The two primary causes for dry mouth are Sjogrens disease and after radiotherapy of a head and neck cancer. Former clinical trials have investigated mesenchymal stem cell treatment for dry mouth with promising results. However, few of the participants evolved normal salivary flow rate. Therefore, in this randomized clinical trial, two treatments of mesenchymal stem cells are administered, 4 months apart. This has not been done before. ...