U.S., Dec. 17 -- ClinicalTrials.gov registry received information related to the study (NCT07285486) titled 'Regenerative Peripheral Nerve Interfaces for the Treatment of Painful Neuromas in Major Limb Amputees' on Dec. 02.
Brief Summary: The Regenerative Peripheral Nerve Interface (RPNI) is a novel strategy to prevent neuroma formation in transected peripheral nerves. The RPNI consists of a residual peripheral nerve that is implanted into a free skeletal muscle graft either at the time of limb amputation or after excision of a terminal neuroma bulb. The sprouting axons of the nerve readily reinnervate the free muscle graft, thereby greatly reducing the chance of neuroma formation.
This investigation has a prospective cohort study design ...