Clinical Trial: Reduction of Edema With a Specialized Cocktail for Ultra-early Management in Intracerebral Hemorrhage

U.S., March 8 -- ClinicalTrials.gov registry received information related to the study (NCT06863558) titled 'Reduction of Edema With a Specialized Cocktail for Ultra-early Management in Intracerebral Hemorrhage' on March 03.

Brief Summary: Intracerebral hemorrhage (ICH) is a severe stroke subtype with high mortality and disability rates, often worsened by perihematomal edema (PHE), which increases intracranial pressure and leads to poor outcomes. Preclinical studies suggest that a pharmacological cocktail (PPA) may help reduce cerebral edema by modulating potassium balance, preserving aquaporin-4 expression, and enhancing lymphatic drainage.

This multicenter, randomized controlled trial (RCT) aims to evaluate the safety and efficacy of PP...