Clinical Trial: Reducing Neoplasia Recurrence After Non-thermal Endoscopic Resection of Large Colorectal Polyps

U.S., Nov. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07242820) titled 'Reducing Neoplasia Recurrence After Non-thermal Endoscopic Resection of Large Colorectal Polyps' on Nov. 17.

Brief Summary: The goal of this clinical trial is to clarify the role of adjuvant thermal ablation for non-thermal endoscopic mucosal resection (EMR) of large (>=20mm) flat colorectal polyps (so-called laterally spreading lesions [LSLs]).

The hypothesis is that adding adjuvant thermal ablation to non-thermal EMR (vs no ablation) will result in lower lesion recurrence rates at 6-month follow-up, and non-inferior adverse events (AE) rates 14 days post EMR.

For participants with planned EMR, endoscopists will perform non-therm...