Clinical Trial: Randomized Comparison of Treatment Guided by Comprehensive Genome and Transcriptome Analysis Versus Standard of Care in Patients with Advanced Rare Cancers (RATIONALE)

U.S., March 4 -- ClinicalTrials.gov registry received information related to the study (NCT06855134) titled 'Randomized Comparison of Treatment Guided by Comprehensive Genome and Transcriptome Analysis Versus Standard of Care in Patients with Advanced Rare Cancers (RATIONALE)' on Feb. 28.

Brief Summary: Rare cancers, defined by an incidence of fewer than 6 cases per 100,000 persons per year, constitute nearly 25% of adult malignancies. They are associated with poor patient outcomes due to incomplete biological understanding and inadequate representation in clinical trials [1]. To address this gap, the DKFZ/NCT/DKTK MASTER (Molecularly Aided Stratification for Tumor Eradication Research) program, developed by NCT and DKFZ, integrates whole-...