U.S., April 3 -- ClinicalTrials.gov registry received information related to the study (NCT06906887) titled 'PULSO Trial: Pulsed Low-Dose-Rate (PLDR) Radiation Chemoradiation (CRT) vs. Standard CRT for Esophageal Cancer' on March 26.
Brief Summary: This is a prospective, randomized, open-label, two-arm phase 2 trial that will evaluate whether the use of Pulsed Low-Dose-Rate radiation technique, as compared to standard radiation, is associated with reduced rates of clinically significant esophagitis during and following chemoradiation.
Study Start Date: June 01
Study Type: INTERVENTIONAL
Condition:
Esophageal Cancer
Oesophageal Cancer
GastroEsophageal Cancer
Intervention:
DRUG: Induction Chemotherapy (modified FLOT or FOLFOX-6)
Subje...