U.S., March 14 -- ClinicalTrials.gov registry received information related to the study (NCT06874673) titled 'Pronase in Improving Endoscopic Mucosal Clarity During Colonoscopy for Patients with Colitis' on March 05.
Brief Summary: Pronase is a proteolytic enzyme known for its ability to clear mucus by breaking down its main component, mucin, through enzymatic hydrolysis. This property makes it useful in gastroscopy, where it is employed to improve the visibility of the mucosal surface during endoscopic examinations. Given the same mechanism, pronase may also be beneficial in enhancing mucosal clarity during colonoscopy. This multicenter, prospective, double-blind randomized controlled trial is designed to assess the effectiveness and safe...