U.S., Jan. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07311707) titled 'Primary Closure vs Open Technique for Pilonidal Sinus' on Dec. 12, 2025.

Brief Summary: The purpose of this randomized controlled trial is to compare two commonly used surgical techniques for the treatment of pilonidal sinus disease: excision with primary closure and excision with open (lay-open) technique. Pilonidal sinus disease is a chronic inflammatory condition of the natal cleft that causes pain, discharge, and functional discomfort, particularly in young adults.

The primary aim of the study is to evaluate whether excision followed by primary closure leads to faster wound healing compared to the open surgical technique. Second...