U.S., Dec. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07265804) titled 'PRF and CGF Scaffolds With EDTA in Regeneration' on Nov. 24.
Brief Summary: This study evaluated the regenerative outcomes of immature permanent teeth with necrotic pulps treated using three scaffold types-blood clot, platelet-rich fibrin (PRF), and concentrated growth factor (CGF)-in combination with either 5% or 17% EDTA as the final irrigant. Thirty teeth were randomly assigned to six treatment groups and monitored clinically and radiographically for 12 months. Cone-beam computed tomography was used to assess root length increase, apical closure, hard-tissue formation, and periapical lesion volume. Clinical findings included the a...