U.S., April 3 -- ClinicalTrials.gov registry received information related to the study (NCT06906757) titled 'Preterm Rupture of Membranes Optimising Antibiotics Trial' on Feb. 18.

Brief Summary: The goal of this clinical trial is to learn which antibiotic regimen works best to prevent infection in pregnant women whose waters break early (preterm, pre-labour rupture of membranes, or PPROM) and assess the health outcomes of babies born to pregnant women who have received these antibiotics.

PROMOAT aims to answer the question: Which antibiotic or combined antibiotic regimen most effectively prevents infection in pregnant women with PPROM < 37+0 weeks' gestation.

Researchers will compare three antibiotic regimens already used in clinical pra...