U.S., Sept. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07196462) titled 'Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia' on Sept. 13.
Brief Summary: The central hypothesis is this: Brain circuits most relevant to cannabis use in schizophrenia are distinct from pathways identified in healthy controls who use cannabis. This study seeks to provide evidence that targeted stimulation of the DMN leads to both altered network activity and a concomitant behavioral change in cue-induced craving and cognitive performance in individuals with schizophrenia and schizoaffective disorder, while targeted stimulation of the L DLPFC leads to these changes in healthy controls who use cannabis. Thi...