U.S., Feb. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07421882) titled 'PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE)' on Dec. 01, 2025.
Brief Summary: The PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE) study is a pilot feasibility trial evaluating the implementation of pre-hospital targeted temperature management (TTM) using a wearable surface cooling device (CarbonCool(R) vest) in adult out-of-hospital cardiac arrest (OHCA) patients with return of spontaneous circulation (ROSC). The study aims to assess feasibility, fidelity, acceptability, and safety of initiating cooling in the field by emergency medical services (EMS) prior to h...