Clinical Trial: POOLED HUMAN PLASMA VS. CRYSTALLOID IN THE MANAGEMENT OF CHILDREN UNDERGOING INSTRUMENTED SPINAL FUSION FOR SCOLIOSIS: A DOUBLE-BLIND, RANDOMIZED CLINICAL TRIAL

U.S., April 19 -- ClinicalTrials.gov registry received information related to the study (NCT06934278) titled 'POOLED HUMAN PLASMA VS. CRYSTALLOID IN THE MANAGEMENT OF CHILDREN UNDERGOING INSTRUMENTED SPINAL FUSION FOR SCOLIOSIS: A DOUBLE-BLIND, RANDOMIZED CLINICAL TRIAL' on April 11.

Brief Summary: OCTAGON trial is a randomized, double-blinded, parallel-group non-inferiority multicenter (Helsinki and Turku University Hospitals, Finland) clinical trial according to CONSORT criteria.

194 adolescents with idiopathic (major curve > 45 degrees) or neuromuscular scoliosis (major curve > 50 degrees) are enrolled for the OCTAGON trial comparing pooled human plasma (Octaplas, 10mL/kg, active management) vs. Plasmalyte (10 mL/kg, placebo) before in...