U.S., Jan. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07313605) titled 'POCUS-Guided Esmolol in Septic Shock: A Pilot RCT' on Dec. 17, 2025.
Brief Summary: The goal of this pilot clinical trial is to determine if conducting a larger study using point-of-care ultrasound (POCUS) to guide beta-blocker therapy in patients with septic shock is feasible. Septic shock is a life-threatening condition where infection causes dangerously low blood pressure, requiring medications to support the heart and circulation. In septic shock, the body's stress response causes the heart to beat too fast, which can worsen organ damage.
Beta-blockers are medications that slow the heart rate and may improve outcomes, but previo...