U.S., Oct. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07207785) titled 'PirtobrUtinib as Frontline Therapy for Elderly Unfit/Frail Patient With MAntle Cell Lymphoma' on Sept. 17.

Brief Summary: This is a prospective, multicenter, phase II study, in elderly patients affected by Mantle cell lymphoma (MCL) defined as unfit/frail according to Simplified Geriatric Assessment (sGA) and previously untreated.

Patients will receive a treatment with Pirtobrutinib monotherapy until tumor progression, unacceptable adverse event, or patient decision for interruption.

Study Start Date: Feb. 01, 2026

Study Type: INTERVENTIONAL

Condition: Mantle Cell Lymphoma

Intervention: DRUG: Pirtobrutinib

Patients will recei...