U.S., Jan. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07366814) titled 'Pipelle Versus Karman Endometrial Biopsy Under Standardized Paracervical Block' on Jan. 03.
Brief Summary: Endometrial biopsy is a commonly used outpatient procedure to evaluate abnormal uterine bleeding and postmenopausal bleeding. Different sampling methods are available, but their diagnostic adequacy and patient experience may vary.
This prospective randomized study compares two commonly used endometrial biopsy methods, Pipelle and Karman cannula, under standardized paracervical block anesthesia. All participants receive the same local anesthetic technique to minimize pain-related differences between methods.
The primary object...