U.S., April 25 -- ClinicalTrials.gov registry received information related to the study (NCT06942039) titled 'Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation' on April 09.
Brief Summary: Pilot study to determine feasibility of adding intrathecal chemotherapy and maintenance therapy after high dose chemotherapy for treatment of newly diagnosed HR-EBTs in patients less than 6 years of age.
Study Start Date: June, 2025
Study Type: INTERVENTIONAL
Condition:
CNS Embryonal Tumor
CNS, Medulloblastoma
Atypical Teratoid Rhabdoid Tumor
Medulloblastoma, Childhood
Medulloblastoma, Group 3
Medulloblastoma, Group 4
Pineoblastoma
Neuroblastoma
Embryonal Tumor With Multilayered Rosettes
Em...