U.S., Nov. 26 -- ClinicalTrials.gov registry received information related to the study (NCT07248878) titled 'Pilot Study for the Generation of Cervical Cancer Organoids From Patients Undergoing Diagnostic Biopsy' on Nov. 18.
Brief Summary: A meta-analysis showed that neoadjuvant chemotherapy followed by radical hysterectomy reduces the risk of mortality by 35% compared to radiotherapy alone, with a 14% increase in five-year survival. Unfortunately, however, approximately 30% of patients undergoing neoadjuvant chemotherapy are referred for adjuvant radiotherapy or chemoradiotherapy due to the presence of high recurrence risk factors after surgery, which results in a bi- or tri-modal treatment with very serious consequences in terms of toxic...