U.S., Jan. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07360574) titled 'Piezo2-related Arthrogryposis & physiopathOLOgy 3' on Dec. 15, 2025.
Brief Summary: Study type: Observational, non-interventional, single-center, descriptive study.
Goal of the study:
The goal of this observational study is to characterize the intensity, variability, and qualitative features of pain in patients with arthrogryposis multiplex congenita (AMC) caused by a gain-of-function mutation in PIEZO2. This population is rare and identified through the French national PARART registry (Pediatric and Adult Registry for patients with ARThrogryposis).
Population:
Participants are >=10 years old, have a genetically confirmed gain-o...