U.S., March 21 -- ClinicalTrials.gov registry received information related to the study (NCT06887907) titled 'Phenotypic and Transcriptomic Description of Megakaryocytes in Sickle Cell Patient' on March 14.
Brief Summary: Sickle cell disease is the most common inherited blood disorder in the world. Chronic hemolysis induces platelet activation and chronic inflammation. Platelets and megakaryocyte, as medullar platelets precursors, are known to play a role in innate immunity. Little is known about the role of megakaryocytes at basal state and during acute complication in sickle cell disease patients. The aim of this study is to evaluate the role of megakaryocytes in sickle cell disease.
Study Start Date: March 13
Study Type: OBSERVATIONAL...