Clinical Trial: Phase 1 Study of the Safety of an Epstein-Barr Virus (EBV) gH/gL/gp42-Ferritin Nanoparticle Vaccine With or Without gp350-Ferritin in Healthy Adults With or Without EBV Infection

U.S., April 4 -- ClinicalTrials.gov registry received information related to the study (NCT06908096) titled 'Phase 1 Study of the Safety of an Epstein-Barr Virus (EBV) gH/gL/gp42-Ferritin Nanoparticle Vaccine With or Without gp350-Ferritin in Healthy Adults With or Without EBV Infection' on April 02.

Brief Summary: Study Description:

This is a phase 1 study to evaluate the safety of a 3-dose vaccination regimen of an adjuvanted EBV gH/gL/gp42-ferritin nanoparticle vaccine with or without gp350-ferritin. Based on data reported in animal studies, our hypothesis is that this EBV vaccine will be safe. In addition, we hypothesize the vaccine will induce a potent immune response that neutralizes EBV infection of B cells and epithelial cells.

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