U.S., July 4 -- ClinicalTrials.gov registry received information related to the study (NCT07049107) titled 'Pharmacokinetics Impact of HRS-8427 on Bupropion and Midazolam in Healthy Subjects' on June 24.

Brief Summary: This study is a single-center, open-label, sequential drug interaction study

The primary objectives are:

To evaluate the pharmacokinetic effects of HRS-8427 injection on the liver drug enzymes CYP2B6 substrate bupropion and CYP3A4 substrate midazolam in healthy subjects.

Study Start Date: July, 2025

Study Type: INTERVENTIONAL

Condition: Health Volunteer

Intervention: DRUG: HRS-8427

HRS-8427

Recruitment Status: NOT_YET_RECRUITING

Sponsor: Jiangsu HengRui Medicine Co., Ltd.

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