U.S., Sept. 16 -- ClinicalTrials.gov registry received information related to the study (NCT07173738) titled 'Pharmacokinetics, Safety and Tolerability of Concurrent Doses of BIA 5-1058 and Furosemide' on Sept. 08.
Brief Summary: The purpose of this study is:
* To assess the effect of BIA 5 1058 400 mg on furosemide pharmacokinetics (PK).
* To assess the effect of furosemide 40 mg on the PK of BIA 5 1058.
Study Start Date: June 11, 2018
Study Type: INTERVENTIONAL
Condition:
Pulmonary Arterial Hypertension
Intervention:
DRUG: BIA 5-1058
During treatment period 1, a single oral dose of BIA 5-1058 (400 mg) will be administered on the morning of day 1, following an overnight fast of at least 10 h.
DRUG: Furosemide
During treatment p...