U.S., May 15 -- ClinicalTrials.gov registry received information related to the study (NCT06972212) titled 'Pharmacodynamic Study of 100mg Suzegtrigine vs Placebo in Healthy Male Adults' on May 06.
Brief Summary: This is a randomized, double-blind, placebo-controlled within-participant crossover study in healthy male participants 18-55 years of age to assess pain tolerance during a cold pressor test.
The study will be conducted at a single center in New Zealand.
Study Start Date: June 04
Study Type: INTERVENTIONAL
Condition:
Pain Detection
Pain Threshold
Intervention:
DRUG: suzetrigine 100mg
Suzetrigine is an inhibitor of the NaV1.8 voltage-gated sodium channel and FDA approved for the treatment of moderate-to-severe acute pain in ...