U.S., April 2 -- ClinicalTrials.gov registry received information related to the study (NCT06904365) titled 'Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women' on March 24.
Brief Summary: Female patients with early onset (<50 years old) pelvic malignancies such as uterine and rectal cancers are rising in incidence, which often requires pelvic radiation; many of these patients are premenopausal and at a high risk of premature ovarian failure from radiotherapy. Premature ovarian failure carries significant cardiac, musculoskeletal, sexual, and psychosocial morbidity. Ovarian transposition carries variable success rates, is not readily accessible to the general population, and can still be at risk of clinically significant radiothera...