U.S., May 9 -- ClinicalTrials.gov registry received information related to the study (NCT06962306) titled 'Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery' on April 30.
Brief Summary: The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following cleft palate surgery in infants and young children.
Study Start Date: May 15
Study Type: INTERVENTIONAL
Condition:
Cleft Palate
Pain
Postoperative Care
Perioperative Care
Children
Intervention:
DRUG: Methadone hydrochloride
Initial dosing 0.2mg/kg, potential to escalate to 0.25mg/kg following interim analysis
DRUG: Fentanyl/Hydromorphone
Per routine care
Recru...