U.S., March 20 -- ClinicalTrials.gov registry received information related to the study (NCT06884540) titled 'Optimizing Patient-centred Outcomes Using Opioid Minimization Strategies: the OPUS Anesthesia Pilot Trial' on March 13.
Brief Summary: Up to 40% of patients experience suboptimal recovery in the days following major surgery, limiting their return to functional independence. Few preventive interventions exist, but intravenous dexmedetomidine and lidocaine administered during general anesthesia represent simple strategies that may significantly impact recovery and other patient-centred outcomes after surgery. The goal of this pilot trial is to determine the feasibility of conducting a phase 3 pragmatic adaptive multicentre trial to e...