U.S., Jan. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07316504) titled 'Optimal Strategy to Correct Stent underexpAnsion in Resistant Lesions' on Sept. 05, 2025.
Brief Summary: Percutaneous coronary intervention (PCI) for in-stent restenosis (ISR) accounts for 5-10% of PCI. ISR may be linked to mechanical complications mainly under-expansion (UE), neointimal hyperplasia and/or neoatherosclerosis. International guidelines recommends non-compliant and very-high-pressure balloons, which lead to sub-optimal angiographic and clinical results. Recently, observational studies have suggested the feasibility and safety of intravascular lithotripsy (IVL) in UE treatment. There are no prospective randomised control...