U.S., Feb. 20 -- ClinicalTrials.gov registry received information related to the study (NCT06834633) titled 'Nephroprotection in Severe Trauma Patients With Kidney Stress' on Nov. 04, 2024.
Brief Summary: Acute Kidney Injury (AKI) occurs in 24% of trauma patients, and is even more common in those with severe trauma. It is a major contributor to morbidity and mortality in trauma. Diagnosis of AKI is based on elevated serum creatinine and decreased urine output, two functional markers already indicating the presence of a significant kidney function impairment. Earlier detection of kidney stress, at a preclinical stage when cellular modifications are still reversible, could reduce the occurrence of AKI episodes if nephroprotective measures ar...