U.S., Dec. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07302321) titled 'Needs of ALS Patients With C9orf72 Mutation and Their Caregivers' on Nov. 28.
Brief Summary: Individuals with Amyotrophic Lateral Sclerosis (ALS) carrying the C9orf72 HRE mutation (C9Pos) often exhibit different phenotypic traits compared to other patients (C9Neg), presenting a more aggressive form of the disease, with also a higher frequency of comorbidity with frontotemporal dementia (ALS-FTD) and a greater prevalence of family history of ALS and/or other neurodegenerative diseases.
Considering these characteristics (comorbidity with FTD and family history of ALS and/or other neurodegenerative pathologies) as factors that have th...