U.S., July 17 -- ClinicalTrials.gov registry received information related to the study (NCT07069426) titled 'Muscle Response to Different Amounts of Dietary Protein During Leg Immobilization' on May 21.
Brief Summary: Individuals who sustain musculoskeletal injuries (MSKI) can experience a rapid loss of muscle mass due to declines in muscle loading and activation that occur post-injury (i.e., disuse atrophy). Loss of muscle under these conditions is attributed to a persistent negative net muscle protein balance (muscle protein synthesis [MPS] < muscle protein breakdown) that results, in part, from declines in postprandial MPS (i.e., anabolic resistance). Nutritional interventions that enhance postprandial MPS may be used to overcome disuse...