U.S., Sept. 24 -- ClinicalTrials.gov registry received information related to the study (NCT07188090) titled 'Mozobil for Autologous Hematopoietic Stem Cell Transplantation' on Sept. 15.
Brief Summary: This prospective trial investigates the approach of G-CSF with risk-adapted Plerixafor use for stem cell mobilization in patients undergoing autologous stem cell transplantation. Since FDA approval in 2008, Plerixafor has been combined with G-CSF to mobilize stem cells, though this regimen has been associated with a potentially higher incidence of engraftment syndrome.
The trial aims to evaluate whether using G-CSF alone, with selective use of Plerixafor, can achieve adequate stem cell collection while possibly reducing the incidence of eng...