U.S., May 2 -- ClinicalTrials.gov registry received information related to the study (NCT06954298) titled 'Molecular Landscape of Complex Lifestyle Modification' on March 30.
Brief Summary: The goal of this clinical trial is to detect the impact of the 3-month complex lifestyle intervention, consisting of dietary counselling, supervised exercise training and cognitive-behavioural intervention in middle-aged sedentary individuals with obesity, specific questions are:
* What is the adaptive response to exercise training on the whole-body and skeletal muscle energy metabolism, insulin sensitivity, metabolic flexibility, muscle functional parameters and cardiopulmonary fitness?
* Would the intensity-related changes of the exercise-induced su...