U.S., Feb. 8 -- ClinicalTrials.gov registry received information related to the study (NCT06814860) titled 'Microenvironmental Trial of Classical Hodgkin Lymphoma in Adolescents' on Jan. 02.
Brief Summary: Background. Classical Hodgkin's lymphoma (cHL) in adolescents between 15 and 18 years shows a higher disease-related mortality and the overall prognosis is worse than both children and adults.
Objectives. To investigate the immune checkpoint inhibitors (ICPI) therapeutic targets and specific T-regulatory and cytotoxic T-cell subsets, in the subgroup of adolescent cHL patients and to investigate their prognostic power.
Methods: Retrieved formalin-fixed paraffin-embedded (FFPE) of adolescent patients diagnosed with cHL with available cli...