U.S., Dec. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07275671) titled 'Microbiome and Premature Ovarian Insufficiency' on Nov. 27.
Brief Summary: This study investigates the differences in gut and vaginal microbiota between women with premature ovarian insufficiency (POI) and healthy volunteers. POI refers to the reduction in ovarian function before the age of 40, leading to irregular or absent menstruation and decreased estrogen levels, which can significantly affect women's reproductive and overall health. Recent research has suggested that gut microorganisms may influence the balance of steroid hormones through various metabolic pathways. Additionally, certain vaginal bacteria appear enriched in pat...