Clinical Trial: Methylprednisolone for Stroke With Large Infarct Core and Post-stroke Lymphocytopenia

U.S., Oct. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07202143) titled 'Methylprednisolone for Stroke With Large Infarct Core and Post-stroke Lymphocytopenia' on Sept. 23.

Brief Summary: The efficacy and safety of early adjunctive methylprednisolone therapy in acute ischemic stroke patients with large infarct cores (ASPECTS score < 6) and post-stroke lymphocytopenia remain unclear. These immunocompromised patients face higher mortality rates and poorer clinical outcomes, with limited effective treatment options currently available. This multicenter, randomized, double-blind, placebo-controlled, non-inferiority trial aims to demonstrate that early methylprednisolone administration combined with reperfusio...