U.S., Nov. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07226245) titled 'Methadone Pharmacokinetics in Cardiac Surgery' on Nov. 04.
Brief Summary: Cardiac surgery frequently leads to significant postoperative pain, with multiple different drug regimens being utilized (both opioid and non-opioid) in an attempt to alleviate this surgical pain. Methadone is currently one of the drugs that is being utilized to help control the pain. It can be given during and/or after surgery. This study hopes to identify the optimal dose of methadone to use to treat this surgical pain.
Study Start Date: Dec., 2025
Study Type: INTERVENTIONAL
Condition:
Postoperative Pain Management
Intervention:
DRUG: Single dose of me...