U.S., Feb. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07380841) titled 'Metformin vs Inositol vs Diet vs Combination Therapy in PCOS' on Jan. 24.
Brief Summary: Polycystic ovary syndrome (PCOS) is a common condition that can cause irregular periods, excess male-type hormones, weight gain, and insulin resistance. This study will compare four commonly used approaches for PCOS management: metformin, inositol, a calorie-restricted diet, and a combination of all three.
A total of 192 women aged 18-35 years with PCOS (diagnosed using Rotterdam criteria) will be randomly assigned to one of four groups for 12 weeks: (A) metformin, (B) myo-inositol plus D-chiro-inositol, (C) calorie-restricted diet, or (D) combi...