U.S., Aug. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07098299) titled 'Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies' on July 10.
Brief Summary: The goal of this clinical trial is to evaluate the safety of Metformin alone and in combination with chemotherapy or immunotherapy in patients with solid tumor cancers. The main questions it aims to answer are:
* what are the toxicities of metformin at multiple dose levels
* what is the maximum tolerated dose of Metformin in combination with chemotherapy or immunotherapy
Participants enrolled will be treated with standard of care chemotherapy and/or immunotherapy in accordance to their disease/stage. In addition, participant...