Clinical Trial: Metabolic and Behavioural Effects of CONTRAVE As Potential Mechanisms of Weight Loss in Adults with Obesity

U.S., Feb. 6 -- ClinicalTrials.gov registry received information related to the study (NCT06809166) titled 'Metabolic and Behavioural Effects of CONTRAVE As Potential Mechanisms of Weight Loss in Adults with Obesity' on Jan. 22.

Brief Summary: Obesity is a common chronic disease linked with increased risk for other illnesses and earlier death. Our team and others have shown that many bodily and psychological changes occur when individuals are on calorie-restricted diets. These changes might undermine dietary adherence and help to explain the relatively poor long-term efficacy of diets. These include increased appetite, increased food 'value' and 'wanting' that leads to overconsumption. Other factors include more sensitive sensory cues (e.g...