Clinical Trial: Melatonin Loaded in Injectable Platelet-Rich Fibrin in the Management Periodontitis

U.S., Jan. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07316582) titled 'Melatonin Loaded in Injectable Platelet-Rich Fibrin in the Management Periodontitis' on Dec. 19, 2025.

Brief Summary: melatonin loaded in injectible platelet rich fibrin in treatment of periodontitis

Study Start Date: Nov. 01, 2025

Study Type: INTERVENTIONAL

Condition: Periodontitis Stage II

Intervention: DRUG: Melatonin-Loaded Injectable Platelet-Rich Fibrin

patients will be included in this group receiving SRP with Melatonin loaded in (I-PRF) using insulin syringe for injection

BIOLOGICAL: injectible platelet rich fibrin (i-PRF )

patients will be included in this group receiving (SRP) with local application of i-PRF

Recru...