U.S., Feb. 13 -- ClinicalTrials.gov registry received information related to the study (NCT06821425) titled 'Melatonin Gel As an Adjuvant in the Surgical Management of Intrabony Defects' on Jan. 08.
Brief Summary: Surgical periodontal therapy is a commonly employed treatment approach aimed at arresting disease progression and promoting tissue regeneration. Despite advancements in surgical techniques, adjunctive therapies are being explored to enhance the outcomes of periodontal surgical debridement. Melatonin, a hormone primarily known for its role in regulating the sleep-wake cycle, has emerged as a promising candidate for periodontal therapy. It possesses potent antioxidant, anti-inflammatory, and immunomodulatory properties, which make ...